October 2, 2024
The 42nd TI-FRIS Hub Meeting / 58th FRIS Hub Meeting (Hybrid event)
TI-FRIS Hub Meetings are held once a month at Tohoku University to foster researchers who understand and can utilize the importance of interdisciplinary research across disciplines and institutions.
Common sense and way of thinking cannot be expected among researchers in different fields. The audience is encouraged to ask questions during the presentation to discuss and deepen their understanding. Please participate actively.
・Date & Time: Every Friday of the month except August (16:00-17:00)
・Target Audience: TI-FRIS Fellows, researchers and students from TI-FRIS participating institutions
The 42nd TI-FRIS Hub Meeting (jointly held with the 58th FRIS Hub Meeting)
Date and Time : Friday, October 25, 2024, 16:00 to 17:00
Event Format:
Hybrid (Online/Zoom・Frontier Research Institute for Interdisciplinary Sciences Seminar room)
Please register to the application form here : Google Form by Thursday, October 24, 2024, 15:00
Please register to the application form here : Google Form by Thursday, October 24, 2024, 15:00
*Depending on the status of the new coronavirus infection, it may be necessary to take measures to prevent the spread of the virus. Please note that there may be changes to online-only sessions, etc. Thank you for your understanding..
*The following persons are eligible to participate
1. Hub Meeting members
Participants targeted for presentation and archived viewing
- FRIS faculty members
- TI-FRIS Fellows
2. Observers
The following participants interested in the Hub Meeting (may also participate in questions and discussions)
The following participants interested in the Hub Meeting (may also participate in questions and discussions)
- Tohoku University DIARE Students
- Staff and students of Tohoku University
- Staff and students of TI-FRIS participating universities
- TI-FRIS officials (committee members, etc.)
- Fellows of “Strategic Professional Development Program for Young Researchers”
- Science Journalists
- Those approved by the Director of FRIS / TI-FRIS Program Manager
Presenter:Associate Professor., Sho KOBAYASHI
(Graduate School of Agricultural Sciences, Yamagata University / Life and Environments /TI-FRIS Fellow)
Presentation Title:Establishment of methods to search for compounds inhibiting iron-dependent cell death, known as ferroptosis, and their application in food extracts
Abstract:Cells are constantly exposed to reactive oxygen species (ROS) due to various stimuli. Excessive ROS cause oxidative damage and are involved in the development of disease such as lifestyle-related diseases. Cells have antioxidant systems in which antioxidant enzymes and antioxidants cooperatively eliminate ROS. Glutathione (GSH) is a major intracellular antioxidant, and its depletion induces to ferroptosis, characterized by the accumulation of lipid peroxides via the Fenton reaction catalyzed by ferrous iron. In this presentation, I will explain the GSH antioxidant system in cells against ROS and introduce methods to search for compounds that inhibit ferroptosis and their application in food extracts.
